Medicines or steroids are often used as treatment when Crohn’s disease first develops to reduce inflammation in the gut. These are usually taken in oral tablet form, or as an enema if the rectum or lower part of the colon are affected.
If the symptoms are severe, a course of steroids may be recommended for a few weeks. In the majority of cases, the symptoms improve within four weeks of starting steroids. Once the symptoms improve, the dose is gradually reduced, and then stopped. Steroids can cause side effects if used over extended periods so they are not usually used as a long-term treatment.
As an alternative to steroids, 5-aminosalicylate medicines can be used to treat mild to moderate symptoms. These types of medicine include sulfasalazine, mesalazine, of salazine, and balsalazide. However, they do not always work and switching to steroids may be necessary if the symptoms are severe.
Some people with Crohn’s disease do not respond well to steroids or 5-aminosalicylate medicines. In these cases, a specialist may advise use of antibiotics to combat infection and immunosuppressive medicines or a combination of these treatments.
If the symptoms are particularly bad and cannot be controlled using medicines, a strict diet may be advised. In most cases, after sticking to the diet for a few weeks, the symptoms improve and a normal diet can be gradually resumed. The reasons why this works are not fully understood, but it is believed that some foods, such as dairy products, may trigger the symptoms and that resting the gut may help.
As a very last resort, if other treatments have not worked, surgery may be required to remove the affected part of the gut. The affected part is removed and the two ends are sewn together. Surgery may also be required to treat complications such as obstructions, abscesses, or damage to the gut.
Other measures may be advised to treat some of the milder symptoms such as anti-diarrhoeal medicines to firm up stools or iron tablets prescribed if anaemia develops. Also, if the gut is not absorbing food properly vitamin supplements may help the body maintain the required vitamin levels.
Painkillers may be needed at times if the symptoms are particularly bad.
On a positive note, giving up smoking will often decrease the frequency of symptoms.




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